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Treatments
In just the last decade, drugs have
been developed that help slow the progress of dementia.
Since 1996 five
new drugs have been approved by the FDA for the treatment of Alzheimer’s
disease and other dementias. Four of these drugs work by slowing the
breakdown of acetylcholine, a brain chemical (neurotransmitter) that is
necessary for memory formation: Cognex, Aricept, Exelon, and Reminyl.
These four drugs all can temporarily improve or stabilize memory and many
studies have shown that they help to slow the decline in mental functions in
patients with Alzheimer's Disease. Although none of these drugs can stop or
reverse the course of Alzheimer's Disease, research shows that the earlier
patients with Alzheimer's Disease begin taking these medications, the longer
they preserve their mental abilities.
Namenda is a
new drug used to treat Alzheimer’s disease that works by regulating
glutamate, another neurotransmitter that is disrupted in Alzheimer's Disease
, and protecting brain cells (neurons) that are lost during Alzheimer's
Disease . Combining Namenda with drugs that promote acetylcholine (i.e.,
Aricept) offers better results than any single drug.
Many other new
treatments are currently being evaluated in clinics around the world. One
new type of drug that researchers believe is showing promise works by
preventing the clumping of beta amyloid proteins, a biochemical process that
is believed to cause the brain pathology in patients with Alzheimer's
Disease. Finally, these drugs can improve intellectual functioning in some
individuals with early vascular dementia or with Lewy body disease. |